A new series of dibutyltin(IV) alkylcyclohexyldithiocarbamates of the type (C4H9)2Sn[S2CNR(C6H11)]2 (R = CH3, C2H5, i-C3H7) have been successfully synthesized using in-situ method. These compounds were characterized by elemental analysis, infrared and 13C NMR spectroscopy. A single crystal X-ray analysis of dibutyltin(IV) ethylcyclohexyldithiocarbamate, (C4H9)2Sn[S2CN(C2H5)(C6H11)]2 (compound 2) showed that the system of this crystal is triclinic with space group P-1 while dibutyltin(IV) methylcyclohexyldithiocarbamate, (C4H9)2Sn[S2CN(CH3)(C6H11)]2 (compound 1) has monoclinic system and it’s space group is P21/c. In the crystal structure of compound 2, the dithiocarbamate ligands are bidentically chelated to the tin atom with non-equivalent of the Sn-S distances: Sn(1)-S(1) = 2.9255(11) and Sn(1)-S(2) = 2.5419(10); Sn(1)-S(3) = 2.8922(9) and Sn(1)-S(4) = 2.5293(10) Å while in compound 1, the dithiocarbamate ligands were anisobidentically chelated to the tin atom.
Saxena, A.K. (1989), Organotin compounds and cancer chemotherapy. Coor. Chem. Reviews 95(1), pp. 109-123.
Pellerito, L. and Nagy, L. (2002), Organotin(IV) n+ complexes formed with biologically active ligands: equilibrium and structural studies, and some biological aspects. Coor. Chem. Reviews 224(1-2), pp. 111-150.
Xanthopoulou, M.N., Hadjikakou, S.K., Hadjiliadis, N., Schürmann, M., Jurkschat, K., Michaelides, A., Skoulika, S., Bakas, T., Binolis, J., Karkabounas, S., and Charalabopoulos, K. (2003), Synthesis, structural characterization and in vitro cytotoxicity of organotin(IV) derivatives of heterocyclic thioamides, 2-mercaptobenzothiazole, 5-chloro-2mercaptobenzothiazole, 3-methyl-2-mercaptobenzothiazole and 2-mercaptonicotinic acid. Journal of Inorg. Biochem. 96(2-3), pp. 425-434.
Sharma, J., Singh, Y.P., and Rai, A.K. (2000), Synthesis, characterization and structural elucidation of monoorgano di(chloro) tin(IV) complexes of heterocyclic dithiocarbamates. Main Group Met. Chem. 23(5), pp. 317-320.
Awang, N., Baba, I., Yusof, M.M.S., and Yamin, B.M. (2003), (N-Cyclohexyl-Nmethyldithiocarbamato)triphenyltin(IV). Acta Cryst, E59, pp. 414-415.
Sharma, J., Singh, Y., Bohra, R., and Rai, A.K. (1996), Synthesis and spectral studies of diorganotin heterocyclic dithiocarbamate complexes: The crystal structure of (CH 3 )2Sn[S 2 CNCH 2 CH 2 CH 2 CH 2 CH 2 ] 2 . Polyhedron, 15(7), pp. 1097-1102.
Siemens (1996), SMART and SAINT. Area Detector Control and Integration Software. Siemens Analytical X-Ray Systems, Inc., Madison, Wisconsin, USA.
Sheldrick, G.M. (1997), SHELXTL V5.1. Software Reference Manual, Bruker AXS, Inc., Madison, Wisconsin, USA. 9. Honda, M., Komura, M., Kawasaki, Y., and Tanaka, T. (1968), Infra-red and PMR spectra of some organotin(IV) N, N-dimethyldithiocarbamates. J. Inorg. Nucl. Chem., 30, pp. 32313237.
Bonati, F. and Ugo, R. (1967), Organotin(IV) N,N-disubstituted dithiocarbamates. J. Organomet. Chem. 10, pp. 257-268.
Farina, Y., Othman, A.H., Baba, I., Ng, S.W., and Fun, H.-K. (2002), Organotin dithiocarbamates derived from hydroxylated amines. Main Group Met. Chem. 25(1), pp. 67-72.